Lomibuvir (VX-222)
Product Specifications
CAS Number
1026785-59-0
Synonyms
VCH-222
Target
HCV Protease
Applications
Proteases
Smiles
CC1CCC (CC1) C (=O) N (C2CCC (CC2) O) C3=C (SC (=C3) C#CC (C) (C) C) C (=O) O
Molecular Formula
C25H35NO4S
Additionnal Information
Lomibuvir (VX-222, VCH-222) is a novel, potent and selective inhibitor of HCV polymerase with IC50 of 0.94-1.2 μM, 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L. Phase 2.
Storage Conditions
2 years -80 in solvent
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