Oligomycin A
Product Specifications
CAS Number
579-13-5
Synonyms
MCH 32
Target
ATPase
Applications
Transmembrane Transporters
Smiles
CCC1CCC2C (C (C (C3 (O2) CCC (C (O3) CC (C) O) C) C) OC (=O) C=CC (C (C (C (=O) C (C (C (C (=O) C (C (C (CC=CC=C1) C) O) (C) O) C) O) C) C) O) C) C
Molecular Formula
C45H74O11
Additionnal Information
Oligomycin A (MCH 32), a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase which inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. It inhibits ATP synthase by blocking its proton channel (Fo subunit), which is necessary for oxidative phosphorylation of ADP to ATP. It also induces apoptosis in a variety of cell types.
Storage Conditions
2 years -80 in solvent
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