Neflamapimod (VX-745)
Product Specifications
CAS Number
209410-46-8
Target
P38 MAPK
Applications
MAPK
Smiles
C1=CC (=C (C (=C1) Cl) C2=C3C=CC (=NN3C=NC2=O) SC4=C (C=C (C=C4) F) F) Cl
Molecular Formula
C19H9Cl2F2N3OS
Additionnal Information
Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.
Storage Conditions
2 years -80 in solvent
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