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Neflamapimod (VX-745)

Product Specifications

CAS Number

209410-46-8

Target

P38 MAPK

Applications

MAPK

Smiles

C1=CC (=C (C (=C1) Cl) C2=C3C=CC (=NN3C=NC2=O) SC4=C (C=C (C=C4) F) F) Cl

Molecular Formula

C19H9Cl2F2N3OS

Additionnal Information

Neflamapimod (VX-745) is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.

Storage Conditions

2 years -80 in solvent

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