PHA-680632
Product Specifications
CAS Number
398493-79-3
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CCC1=C (C (=CC=C1) CC) NC (=O) N2CC3=C (C2) NN=C3NC (=O) C4=CC=C (C=C4) N5CCN (CC5) C
Molecular Formula
C28H35N7O2
Additionnal Information
PHA-680632 is a potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Storage Conditions
2 years -80 in solvent
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