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PHA-680632

Product Specifications

CAS Number

398493-79-3

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CCC1=C (C (=CC=C1) CC) NC (=O) N2CC3=C (C2) NN=C3NC (=O) C4=CC=C (C=C4) N5CCN (CC5) C

Molecular Formula

C28H35N7O2

Additionnal Information

PHA-680632 is a potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.

Storage Conditions

2 years -80 in solvent

Frequently Asked Questions

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