Ispinesib (SB-715992)
Product Specifications
CAS Number
336113-53-2
Synonyms
CK0238273
Target
Kinesin
Applications
Cytoskeletal Signaling
Smiles
CC1=CC=C (C=C1) C (=O) N (CCCN) C (C2=NC3=C (C=CC (=C3) Cl) C (=O) N2CC4=CC=CC=C4) C (C) C
Molecular Formula
C30H33ClN4O2
Additionnal Information
Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1.7 nM in a cell-free assay, no inhibition to CENP-E, RabK6, MCAK, MKLP1, KHC or Kif1A. Ispinesib induces mitotic arrest and apoptotic cell death.
Storage Conditions
2 years -80 in solvent
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