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Mizoribine

Product Specifications

CAS Number

50924-49-7

Synonyms

NSC 289637, HE 69

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

C1=NC (=C (N1C2C (C (C (O2) CO) O) O) O) C (=O) N

Molecular Formula

C9H13N3O6

Additionnal Information

Mizoribine is an imidazole nucleoside and an immunosuppressant that inhibits HCV RNA replication with IC50 of ~ 100 μM for anti-HCV activity. Mizoribine is a selective inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH) and guanosine monophosphate synthetase. Mizoribine also inhibits SARS-CoV.

Storage Conditions

2 years -80 in solvent

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