MGCD-265 analog
Product Specifications
CAS Number
875337-44-3
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (N=C1) C2=CC3=NC=CC (=C3S2) OC4=C (C=C (C=C4) NC (=S) NC (=O) CC5=CC=CC=C5) F
Molecular Formula
C26H20FN5O2S2
Additionnal Information
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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