Ketoconazole
Product Specifications
CAS Number
65277-42-1
Synonyms
R 41400
Target
P450 (e.g. CYP17)
Applications
Metabolism
Smiles
CC (=O) N1CCN (CC1) C2=CC=C (C=C2) OCC3COC (O3) (CN4C=CN=C4) C5=C (C=C (C=C5) Cl) Cl
Molecular Formula
C26H28Cl2N4O4
Additionnal Information
Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.
Storage Conditions
2 years -80 in solvent
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