Camptothecin (CPT)
Product Specifications
CAS Number
7689-03-4
Synonyms
Campathecin, (S) - (+) -Camptothecin, NSC-100880
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
CCC1 (C2=C (COC1=O) C (=O) N3CC4=CC5=CC=CC=C5N=C4C3=C2) O
Molecular Formula
C20H16N2O4
Additionnal Information
Camptothecin (CPT) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM in a cell-free assay. Camptothecin induces apoptosis in cancer cells via microRNA-125b-mediated mitochondrial pathways. Phase 2.
Storage Conditions
2 years -80 in solvent
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