XL228

Product Specifications

CAS Number

898280-07-4

Target

Bcr-Abl

Applications

Protein Tyrosine Kinase

Smiles

CC (C) C1=NOC (=C1) CNC2=NC (=CC (=N2) N3CCN (C) CC3) NC4=N[NH]C (=C4) C5CC5

Molecular Formula

C22H31N9O

Additionnal Information

XL228 is a protein kinase inhibitor with IC50 of 5 nM, 1.4 nM, 3.1 nM, 1.6 nM, 6.1 nM and 2 nM for wild-type ABL kinase, ABL T315I, Aurora A, IGF-1R, SRC and LYN, respectively.

Storage Conditions

3 years -20°C powder

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