WYE-354
Product Specifications
CAS Number
1062169-56-5
Target
MTOR
Applications
PI3K/Akt/mTOR
Smiles
COC (=O) NC1=CC=C (C=C1) C2=NC3=C (C=NN3C4CCN (CC4) C (=O) OC) C (=N2) N5CCOCC5
Molecular Formula
C24H29N7O5
Additionnal Information
WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) not P-AKT (T308), selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .
Storage Conditions
2 years -80 in solvent
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