What is the catalog number for PD173074?

The catalog number for PD173074 is C07667-50mg.

What sizes are available for PD173074?

PD173074 is available in the following size(s): 50 mg.

Is PD173074 in stock?

PD173074 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for PD173074?

PD173074 is requires dry ice shipping.

PD173074

Product Specifications

CAS Number

219580-11-7

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CCN (CC) CCCCNC1=NC2=NC (=C (C=C2C=N1) C3=CC (=CC (=C3) OC) OC) NC (=O) NC (C) (C) C

Molecular Formula

C28H41N7O3

Additionnal Information

PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells.