Leflunomide
Product Specifications
CAS Number
75706-12-6
Synonyms
HWA486, RS-34821, SU101
Target
Dehydrogenase
Applications
Metabolism
Smiles
CC1=C (C=NO1) C (=O) NC2=CC=C (C=C2) C (F) (F) F
Molecular Formula
C12H9F3N2O2
Additionnal Information
Leflunomide is a pyrimidine synthesis and protein tyrosine kinase inhibitor belonging to the DMARD, used as an immunosuppressant agent. The active metabolite of Leflunomide is A77 1726, which inhibits dihydroorotate dehydrogenase (DHODH) . Leflunomide is also an agonist of the AhR.
Storage Conditions
2 years -80 in solvent
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