Topotecan HCl
Product Specifications
CAS Number
119413-54-6
Synonyms
Nogitecan HCl, SKFS 104864A, NSC 609699
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
CCC1 (C2=C (COC1=O) C (=O) N3CC4=CC5=C (C=CC (=C5CN (C) C) O) N=C4C3=C2) O.Cl
Molecular Formula
C23H23N3O5.HCl
Additionnal Information
Topotecan HCl is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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