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Etoposide

Product Specifications

CAS Number

33419-42-0

Synonyms

VP-16213, VP-16

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

CC1OCC2C (O1) C (C (C (O2) OC3C4COC (=O) C4C (C5=CC6=C (C=C35) OCO6) C7=CC (=C (C (=C7) OC) O) OC) O) O

Molecular Formula

C29H32O13

Additionnal Information

Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding. Etoposide induces autophagy, mitophagy and apoptosis.

Storage Conditions

2 years -80 in solvent

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