Etoposide
Product Specifications
CAS Number
33419-42-0
Synonyms
VP-16213, VP-16
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
CC1OCC2C (O1) C (C (C (O2) OC3C4COC (=O) C4C (C5=CC6=C (C=C35) OCO6) C7=CC (=C (C (=C7) OC) O) OC) O) O
Molecular Formula
C29H32O13
Additionnal Information
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding. Etoposide induces autophagy, mitophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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