Carboplatin
Product Specifications
CAS Number
41575-94-4
Synonyms
NSC 241240, JM-8, CBDCA
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1CC (C1) (C (=O) O) C (=O) O.[NH2-].[NH2-].[Pt+2]
Molecular Formula
C6H12N2O4Pt
Additionnal Information
Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
Storage Conditions
2 years -80 in solvent
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