Bleomycin sulfate
Product Specifications
CAS Number
9041-93-4
Synonyms
NSC125066 sulfate
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
CC1=C (N=C (N=C1N) C (CC (=O) N) NCC (C (=O) N) N) C (=O) NC (C (C2=CN=CN2) OC3C (C (C (C (O3) CO) O) O) OC4C (C (C (C (O4) CO) O) OC (=O) N) O) C (=O) NC (C) C (C (C) C (=O) NC (C (C) O) C (=O) NCCC5=NC (=CS5) C6=NC (=CS6) C (=O) NCCC[S+] (C) C) O.OS (=O) (=O) [O-]
Molecular Formula
C55H85N17O25S4
Additionnal Information
Bleomycin sulfate is a glycopeptide antibiotic and a DNA synthesis inhibitor, as well as an anticancer agent for squamous cell carcinomas (SCC) with an IC50 of 4 nM in UT-SCC-19A cells. Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin (NSC125066) sulfate can be used to induce animal models of pulmonary fibrosis.
Storage Conditions
2 years -80 in solvent
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