Decitabine (5-Aza-2'-Deoxycytidine)
Product Specifications
CAS Number
2353-33-5
Synonyms
Deoxycytidine, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR, NSC 127716
Target
DNA Methyltransferase
Applications
Epigenetics
Smiles
C1C (C (OC1N2C=NC (=NC2=O) N) CO) O
Molecular Formula
C8H12N4O4
Additionnal Information
Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS) . Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.
Storage Conditions
2 years -80 in solvent
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