CUDC-101
Product Specifications
CAS Number
1012054-59-9
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=C2C (=C1) N=CN=C2NC3=CC=CC (=C3) C#C) OCCCCCCC (=O) NO
Molecular Formula
C24H26N4O4
Additionnal Information
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
Storage Conditions
2 years -80 in solvent
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