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BIBR 1532

Product Specifications

CAS Number

321674-73-1

Target

Telomerase

Applications

DNA Damage/DNA Repair

Smiles

CC (=CC (=O) NC1=CC=CC=C1C (=O) O) C2=CC3=CC=CC=C3C=C2

Molecular Formula

C21H17NO3

Additionnal Information

BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase are observed at concentrations vastly exceeding the IC50 for telomerase. BIBR 1532 induces apoptosis in cancer cells.

Storage Conditions

2 years -80 in solvent

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