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Danoprevir

Product Specifications

CAS Number

850876-88-9

Synonyms

ITMN-191, RG7227

Target

HCV Protease

Applications

Proteases

Smiles

CC (C) (C) OC (=O) NC1CCCCCC=CC2CC2 (NC (=O) C3CC (CN3C1=O) OC (=O) N4CC5=C (C4) C (=CC=C5) F) C (=O) NS (=O) (=O) C6CC6

Molecular Formula

C35H46FN5O9S

Additionnal Information

Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.

Storage Conditions

2 years -80 in solvent

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