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XAV-939

Product Specifications

CAS Number

284028-89-3

Synonyms

NVP-XAV939

Target

Wnt/beta-catenin

Applications

Cytoskeletal Signaling

Smiles

C1CSCC2=C1N=C (NC2=O) C3=CC=C (C=C3) C (F) (F) F

Molecular Formula

C14H11F3N2OS

Additionnal Information

XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.

Storage Conditions

2 years -80 in solvent

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