XAV-939
Product Specifications
CAS Number
284028-89-3
Synonyms
NVP-XAV939
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Smiles
C1CSCC2=C1N=C (NC2=O) C3=CC=C (C=C3) C (F) (F) F
Molecular Formula
C14H11F3N2OS
Additionnal Information
XAV-939 (NVP-XAV939) selectively inhibits Wnt/β-catenin-mediated transcription through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM in cell-free assays, regulates axin levels and does not affect CRE, NF-κB or TGF-β.
Storage Conditions
2 years -80 in solvent
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