CYC116
Product Specifications
CAS Number
693228-63-6
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
CC1=C (SC (=N1) N) C2=NC (=NC=C2) NC3=CC=C (C=C3) N4CCOCC4
Molecular Formula
C18H20N6OS
Additionnal Information
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.
Storage Conditions
2 years -80 in solvent
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