WZ3146
Product Specifications
CAS Number
1214265-56-1
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC=C (C (=N3) OC4=CC=CC (=C4) NC (=O) C=C) Cl
Molecular Formula
C24H25ClN6O2
Additionnal Information
WZ3146 is a mutant-selective irreversible inhibitor of EGFR (L858R) and EGFR (E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I) .
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
363089 200 µL
FDPS (Farnesyl Diphosphate Synthase, FPS, Farnesyl Pyrophosphate Synthetase, Dimethylallyltranstransferase, Geranyltranstransferase)
Sign In for Pricing
View Details 
TA807225AM 100 µL
Factor XII (F12) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2D12]
Sign In for Pricing
View Details 124023-FITC 100 µL
BSND (Barttin, Bartter Syndrome, Infantile, with Sensorineural Deafness, BART, DFNB73, MGC119283, MGC119284, MGC119285) (FITC)
Sign In for Pricing
View Details