ABT-751 (E7010)

Product Specifications

CAS Number

141430-65-1

Target

Microtubule Associated

Applications

Cytoskeletal Signaling

Smiles

COC1=CC=C (C=C1) S (=O) (=O) NC2=C (N=CC=C2) NC3=CC=C (C=C3) O

Molecular Formula

C18H17N3O4S

Additionnal Information

ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules, not a substrate for the MDR transporter and is active against cell lines resistant to vincristine, doxorubicin, and cisplatin. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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