MK-8245
Product Specifications
CAS Number
1030612-90-8
Target
SCD
Applications
Metabolism
Smiles
C1CN (CCC1OC2=C (C=CC (=C2) F) Br) C3=NOC (=C3) C4=NN (N=N4) CC (=O) O
Molecular Formula
C17H16BrFN6O4
Additionnal Information
MK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2.
Storage Conditions
2 years -80 in solvent
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