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Cyclopamine

Product Specifications

CAS Number

4449-51-8

Synonyms

11-deoxojervine

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

CC1CC2C (C (C3 (O2) CCC4C5CC=C6CC (CCC6 (C5CC4=C3C) C) O) C) NC1

Molecular Formula

C27H41NO2

Additionnal Information

Cyclopamine (11-deoxojervine) is a specific Hedgehog (Hh) signaling pathway antagonist of Smoothened (Smo) with IC50 of 46 nM in TM3Hh12 cells.

Storage Conditions

2 years -80 in solvent

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