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Ivacaftor (VX-770)

Product Specifications

CAS Number

873054-44-5

Synonyms

VX-770

Target

CFTR

Applications

Transmembrane Transporters

Smiles

CC (C) (C) C1=CC (=C (C=C1NC (=O) C2=CNC3=CC=CC=C3C2=O) O) C (C) (C) C

Molecular Formula

C24H28N2O3

Additionnal Information

Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.

Storage Conditions

2 years -80 in solvent

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