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Alvespimycin (17-DMAG) HCl

Product Specifications

CAS Number

467214-21-7

Synonyms

NSC 707545, BMS 826476 HCl, KOS 1022

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CC1CC (C (C (C=C (C (C (C=CC=C (C (=O) NC2=CC (=O) C (=C (C1) C2=O) NCCN (C) C) C) OC) OC (=O) N) C) C) O) OC.Cl

Molecular Formula

C32H48N4O8•HCl

Additionnal Information

Alvespimycin (17-DMAG, NSC 707545, BMS 826476, KOS 1022) HCl is a potent HSP90 inhibitor with IC50 of 62 nM in a cell-free assay.

Storage Conditions

2 years -80 in solvent

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