What is the catalog number for Sepantronium Bromide (YM155)?

The catalog number for Sepantronium Bromide (YM155) is C07545-1g.

What sizes are available for Sepantronium Bromide (YM155)?

Sepantronium Bromide (YM155) is available in the following size(s): 1 g.

Is Sepantronium Bromide (YM155) in stock?

Sepantronium Bromide (YM155) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Sepantronium Bromide (YM155)?

Sepantronium Bromide (YM155) is requires dry ice shipping.

Sepantronium Bromide (YM155)

Product Specifications

CAS Number

781661-94-7

Target

Survivin

Applications

Apoptosis

Smiles

CC1=[N+] (C2=C (N1CCOC) C (=O) C3=CC=CC=C3C2=O) CC4=NC=CN=C4.[Br-]

Molecular Formula

C20H19BrN4O3

Additionnal Information

Sepantronium Bromide (YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells. Phase 2.