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BMS-754807

Product Specifications

CAS Number

1001350-96-4

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CC1 (CCCN1C2=NN3C=CC=C3C (=N2) NC4=NNC (=C4) C5CC5) C (=O) NC6=CN=C (C=C6) F

Molecular Formula

C23H24FN9O

Additionnal Information

BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met (c-Met), Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.

Storage Conditions

2 years -80 in solvent

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