Mocetinostat (MGCD0103)
Product Specifications
CAS Number
726169-73-9
Synonyms
MG0103
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
C1=CC=C (C (=C1) N) NC (=O) C2=CC=C (C=C2) CNC3=NC=CC (=N3) C4=CN=CC=C4
Molecular Formula
C23H20N6O
Additionnal Information
Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2.
Storage Conditions
2 years -80 in solvent
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