Everolimus
Product Specifications
CAS Number
159351-69-6
Synonyms
RAD001, SDZ-RAD
Target
MTOR
Applications
PI3K/Akt/mTOR
Smiles
CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) OCCO) C) C) O) OC) C) C) C) OC
Molecular Formula
C53H83NO14
Additionnal Information
Everolimus is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM in a cell-free assay. Everolimus induces cell apoptosis and autophagy and inhibits tumor cells proliferation.
Storage Conditions
2 years -80 in solvent
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