Triciribine (API-2)
Product Specifications
CAS Number
35943-35-2
Synonyms
NSC 154020, VD-0002, vqd-002, TCN
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CN1C2=NC=NC3=C2C (=CN3C4C (C (C (O4) CO) O) O) C (=N1) N
Molecular Formula
C13H16N6O4
Additionnal Information
Triciribine (API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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