TAE684 (NVP-TAE684)
Product Specifications
CAS Number
761439-42-3
Target
ALK
Applications
Protein Tyrosine Kinase
Smiles
CC (C) S (=O) (=O) C1=CC=CC=C1NC2=NC (=NC=C2Cl) NC3=C (C=C (C=C3) N4CCC (CC4) N5CCN (CC5) C) OC
Molecular Formula
C30H40ClN7O3S
Additionnal Information
TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor which blocked the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM, 100-fold more sensitive for ALK than InsR. TAE684 (NVP-TAE684) induces cell cycle arrest and apoptosis.
Storage Conditions
2 years -80 in solvent
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