What is the catalog number for Danusertib (PHA-739358)?

The catalog number for Danusertib (PHA-739358) is C16114-10mM/1mL.

What sizes are available for Danusertib (PHA-739358)?

Danusertib (PHA-739358) is available in the following size(s): 10 mM/1mL.

Is Danusertib (PHA-739358) in stock?

Danusertib (PHA-739358) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Danusertib (PHA-739358)?

Danusertib (PHA-739358) is requires dry ice shipping.

Danusertib (PHA-739358)

Product Specifications

CAS Number

827318-97-8

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CN1CCN (CC1) C2=CC=C (C=C2) C (=O) NC3=NNC4=C3CN (C4) C (=O) C (C5=CC=CC=C5) OC

Molecular Formula

C26H30N6O3

Additionnal Information

Danusertib (PHA-739358) is an Aurora kinase inhibitor for Aurora A/B/C with IC50 of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc. Danusertib induces apoptosis, cell cycle arrest, and autophagy. Phase 2.