U0126-EtOH
Product Specifications
CAS Number
1173097-76-1
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CCO.C1=CC=C (C (=C1) N) SC (=C (C#N) C (=C (N) SC2=CC=CC=C2N) C#N) N
Molecular Formula
C18H16N6S2.C2H6O
Additionnal Information
U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.
Storage Conditions
2 years -80 in solvent
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