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MLN8054

Product Specifications

CAS Number

869363-13-3

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

C1C2=CN=C (N=C2C3=C (C=C (C=C3) Cl) C (=N1) C4=C (C=CC=C4F) F) NC5=CC=C (C=C5) C (=O) O

Molecular Formula

C25H15ClF2N4O2

Additionnal Information

MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM in Sf9 insect cell. It is more than 40-fold selective for Aurora A than Aurora B. Phase 1.

Storage Conditions

2 years -80 in solvent

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