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GSK1904529A

Product Specifications

CAS Number

1089283-49-7

Synonyms

GSK 4529

Target

IGF-1R

Applications

Protein Tyrosine Kinase

Smiles

CCC1=CC (=C (C=C1N2CCC (CC2) N3CCN (CC3) S (=O) (=O) C) OC) NC4=NC=CC (=N4) C5=C (N=C6N5C=CC=C6) C7=CC (=C (C=C7) OC) C (=O) NC8=C (C=CC=C8F) F

Molecular Formula

C44H47F2N9O5S

Additionnal Information

GSK1904529A (GSK 4529) is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM in cell-free assays, >100-fold more selective for IGF-1R/InsR than Akt1/2, Aurora A/B, B-Raf, CDK2, EGFR etc.

Storage Conditions

2 years -80 in solvent

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