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Abexinostat (PCI-24781)

Product Specifications

CAS Number

783355-60-2

Synonyms

CRA-024781

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

CN (C) CC1=C (OC2=CC=CC=C21) C (=O) NCCOC3=CC=C (C=C3) C (=O) NO

Molecular Formula

C21H23N3O5

Additionnal Information

Abexinostat (PCI-24781, CRA-024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.

Storage Conditions

2 years -80 in solvent

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