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NVP-ADW742

Product Specifications

CAS Number

475488-23-4

Synonyms

GSK 552602A, ADW742

Target

IGF-1R

Applications

Protein Tyrosine Kinase

Smiles

C1CCN (C1) CC2CC (C2) N3C=C (C4=C (N=CN=C43) N) C5=CC (=CC=C5) OCC6=CC=CC=C6

Molecular Formula

C28H31N5O

Additionnal Information

NVP-ADW742 (GSK 552602A) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.

Storage Conditions

2 years -80 in solvent

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