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Brivanib (BMS-540215)

Product Specifications

CAS Number

649735-46-6

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=CC2=C (N1) C=CC (=C2F) OC3=NC=NN4C3=C (C (=C4) OCC (C) O) C

Molecular Formula

C19H19FN4O3

Additionnal Information

Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.

Storage Conditions

2 years -80 in solvent

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