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Vismodegib (GDC-0449)

Product Specifications

CAS Number

879085-55-9

Synonyms

GDC-0449

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

CS (=O) (=O) C1=CC (=C (C=C1) C (=O) NC2=CC (=C (C=C2) Cl) C3=CC=CC=N3) Cl

Molecular Formula

C19H14Cl2N2O3S

Additionnal Information

Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.

Storage Conditions

2 years -80 in solvent

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