SU11274
Product Specifications
CAS Number
658084-23-2
Synonyms
PKI-SU11274
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (NC (=C1C (=O) N2CCN (CC2) C) C) C=C3C4=C (C=CC (=C4) S (=O) (=O) N (C) C5=CC (=CC=C5) Cl) NC3=O
Molecular Formula
C28H30CIN5O4S
Additionnal Information
SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.
Storage Conditions
2 years -80 in solvent
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