What is the catalog number for Adezmapimod (SB203580)?

The catalog number for Adezmapimod (SB203580) is C16092-200mg.

What sizes are available for Adezmapimod (SB203580)?

Adezmapimod (SB203580) is available in the following size(s): 200 mg.

Is Adezmapimod (SB203580) in stock?

Adezmapimod (SB203580) is currently made to order / not held in immediate stock. Contact us for lead time.

Adezmapimod (SB203580)

Product Specifications

CAS Number

152121-47-6

Synonyms

RWJ 64809, PB 203580

Target

P38 MAPK

Applications

MAPK

Smiles

CS (=O) C1=CC=C (C=C1) C2=NC (=C (N2) C3=CC=NC=C3) C4=CC=C (C=C4) F

Molecular Formula

C21H16FN3OS

Additionnal Information

Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3 (106T) and SAPK4 (106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy.