Adezmapimod (SB203580)
Product Specifications
CAS Number
152121-47-6
Synonyms
RWJ 64809, PB 203580
Target
P38 MAPK
Applications
MAPK
Smiles
CS (=O) C1=CC=C (C=C1) C2=NC (=C (N2) C3=CC=NC=C3) C4=CC=C (C=C4) F
Molecular Formula
C21H16FN3OS
Additionnal Information
Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3 (106T) and SAPK4 (106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy.
Storage Conditions
3 years-20°C (in the dark) powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1001981-01 0.02 mg (E-Coli)
Recombinant Francisella tularensis subsp. mediasiatica Glucose-1-phosphate adenylyltransferase (glgC)
Sign In for Pricing
View Details MBS1001981-02 0.02 mg (Yeast)
Recombinant Francisella tularensis subsp. mediasiatica Glucose-1-phosphate adenylyltransferase (glgC)
Sign In for Pricing
View Details MBS1001981-03 0.1 mg (E-Coli)
Recombinant Francisella tularensis subsp. mediasiatica Glucose-1-phosphate adenylyltransferase (glgC)
Sign In for Pricing
View Details MBS1001981-04 0.1 mg (Yeast)
Recombinant Francisella tularensis subsp. mediasiatica Glucose-1-phosphate adenylyltransferase (glgC)
Sign In for Pricing
View Details MBS1001981-05 0.02 mg (Baculovirus)
Recombinant Francisella tularensis subsp. mediasiatica Glucose-1-phosphate adenylyltransferase (glgC)
Sign In for Pricing
View Details MBS1001981-06 0.02 mg (Mammalian-Cell)
Recombinant Francisella tularensis subsp. mediasiatica Glucose-1-phosphate adenylyltransferase (glgC)
Sign In for Pricing
View Details